Company Description Provide methodological support for ACMG’s evidence-based guidelines program. Conduct systematic reviews based upon IOM (National Academies) standards and develop clinical practice guidelines using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. This includes, but is not limited to, development of clinical questions, development and completion of literature searches, data extraction, assessment of study quality, meta-analyses, completion of evidence profiles and “evidence to decision” tables, and development of final guideline recommendation statements. Coordinate guideline development, dissemination, and implementation efforts with the volunteer Topic Selection Committee and to